From 2014 to 2018, he studied at the bachelor’s level at the Faculty of "Foreign Language and Literature (English Language)" of the Uzbekistan State University of World Languages. In 2018, he was admitted to the master’s program of the same university and graduated in 2020.

He began his professional career in 2018–2019 as an English teacher at General Secondary School No. 13 in the Zangiota district of Tashkent Province. From 2019 to 2021, he worked as an English teacher at the Department of Foreign Languages at Puchon University in Tashkent. From 2020 to 2023, he held positions as a trainee teacher, teacher, and senior teacher at the Tashkent State University of Uzbek Language and Literature named after Alisher Navoi. Since 2023, he has been working at Renaissance Education University as an associate professor and head of a department.

On October 29, 2022, Khursanov Nurislom Iskandarovich successfully defended his dissertation for the degree of Doctor of Philosophy (PhD) in Philological Sciences on the topic "The Relationship of Verbal and Nonverbal Components in Dramatic Discourse (Based on Works in Uzbek and English)" at the Academic Council No. PhD.03/30.12.2019.Phil.60.02 under Andijan State University, specializing in 10.00.06-Comparative Literature, Contrastive Linguistics, and Translation Studies.

On August 28, 2024, based on the recommendation of the Council of Renaissance Education University, he was awarded the academic title of Associate Professor by the Higher Attestation Commission (HAC).

N. Khursanov has continued his scientific research, achieving a number of accomplishments. Notably, on December 28, 2024, he successfully defended his dissertation for the degree of Doctor of Philological Sciences (DSc) on the topic "Dramatic Discourse: Cognitive, Pragmatic, and Linguocultural Description (A Comparison of English and Uzbek Languages)" at the Academic Council No. DSc.03/30.12.2019.Phil.05.02 under Ferghana State University, specializing in 10.00.06—Comparative Literature, Contrastive Linguistics, and Translation Studies.

Additionally, he actively participated in the applied project No. I-OT-2019-42, carried out in 2021-2023 at the Tashkent State University of Uzbek Language and Literature named after Alisher Navoi, titled "Creation of a Multilingual (Uzbek, Russian, English) Electronic Platform for Uzbek Literature," as well as in the applied project No. AM-FZ-201908172, planned for 2020-2022, titled "Creation of an Educational Corpus of the Uzbek Language."

N. Khursanov has authored 1 scientific monograph, 5 educational-methodological manuals, 3 scientific articles published in journals included in the first quartile (Q1) of the Scopus database, and more than 50 scientific articles published in local and international journals.